Human and Macaque Monkey Cerebellum Unfolding Movies
From:
Sereno, M.I., J. Diedrichsen, M. Tachrount, G. Testa-Silva, H. d'Arceuil,
and C. De Zeeuw (2020)
The human cerebellum has almost 80% of the surface area of the neocortex.
Proceedings of the National Academy of Sciences USA 117:19538-19543.
(doi: 10.1073/pnas.2002896117)
Article PDF
Supplementary Text
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In This Issue...
Movie S1 (loop)
Unfolding and refolding the reconstructed surface of the middle
layers of human cerebellar cortex (movie loop). The initially
folded reconstruction rotates, unfolds, and then refolds,
first in posterior, then in anterior view. The deep fissures
between the lobules are revealed as the surface unfolds. The
near-midline cerebellar tonsils are visible in the anterior
view (at 00:25 to 00:30). Because of the substantial intrinsic
curvature of the cerebellar surface, the unfolded 'bubbles'
formed by each lobule cannot be further unfolded/inflated
without severe distortion.
https://mri.sdsu.edu/sereno/cereb/movies/sereno-human-cereb-unfold.mov
Movie S2 (loop)
Unfolding and refolding the reconstructed surface of the
middle layers of macaque monkey cerebellar cortex (movie
loop). The initially folded reconstruction rotates, unfolds,
and refolds in parallel with the first movie (SI Appendix,
Movie S1). By comparing the two movies, the huge expansion of
the hemispheres relative to the vermis in humans, especially
posteriorly, is quite apparent. Note that the much smaller
monkey surface is not to same scale as the human surface
(see Fig. 2 for true relative sizes of the surfaces).
https://mri.sdsu.edu/sereno/cereb/movies/sereno-monk-cereb-unfold.mov
Cut lateral hemisphere rotates (loop)
The lateral half of the right hemisphere has been cut off and then
rotated to allow viewing the complexly folded surface from the inside
(white).
https://mri.sdsu.edu/sereno/cereb/movies/sereno-human-cereb-cut.mp4
Spherical morph rotates (loop)
A spherical morph of the entire cerebellar surface rotates, starting
from an anterior (ventral) view, with the cut peduncles, the flocculi,
the tonsils, and the vermis visible. Note that the representation here of
the original local surface area is
extremely distorted because of
the large and locally variable amount of intrinsic (Gaussian) curvature.
https://mri.sdsu.edu/sereno/cereb/movies/sereno-human-cereb-sphererot.mp4
(N.B.: the S1/S2 movies are L/R mirror images of sample cerebellum)
(N.B.: QuickTime Player can L/R flip)